OC-037 Triclosan-coated sutures decrease the risk of surgical site infection in abdominal surgery. A systematic review and meta-analysis

Abstract Aim Surgical site infection (SSI) occurs in 2–10% of the patients after abdominal surgery and has an impact on morbidity, mortality medical costs. The aim this systematic review meta-analysis was to evaluate whether use triclosan-coated sutures for fascial closure adominal decrease rate SSI compared uncoated sutures. Methods A conducted using PRISMA guidelines. literature search performed Medline ALL, Web Science Core Collection, Cochrane Central Register Controlled Trials Embase. latest January, 21th, 2023. Risk bias assessed RoB 2 tool. pooled RevMan. Results Out 1356 records, ten Randomized Trials, with a total 9432 were included: 4763 Triclosan-coated group 4660 group. overall significantly reduced Odds Ratio (OR) 0.84 (95% CI [0.76; 0.94] p = 0.002). If PDS evaluated separately (PDS Plus 3999, 3900), triclosan-coating OR 0.86 [0.77; 0.96], 0.008). When Vicryl (Vicryl 764, 760), 0.71 [0.48; 1.04], 0.08) not significant. Conclusions In current meta-analysis, it found that incidence SSIs decreases when are used closure,